HBME-1 Immunostaining in Thyroid Tumors Especially in Follicular Neoplasm
نویسندگان
چکیده
منابع مشابه
"monoclonal antibody hbme-1 usefulness in differentiation of benign neoplasm and differentiated thyroid carcinoma"
hbme-l is an antimesothelial monoclonal antibody that recognizes an unknown antigen on microvilli of mesothelial cells. the antibody is only relatively specific for mesothelium and is used in the differential diagnosis of mesothelioma and adenocarcinoma within the context of an appropriate immuno-histochemical panel. hbme-l has also been reported to strongly and uniformly stain papillary and fo...
متن کاملUsefulness of HBME-1, cytokeratin 19 and galectin-3 immunostaining in the diagnosis of thyroid malignancy.
AIMS To investigate the usefulness of immunohistochemical expression and immunolocalization of a panel of thyroid malignancy markers including HBME-1, cytokeratin (CK) 19 and galectin-3. METHODS AND RESULTS We evaluated 170 thyroid lesions including 148 neoplastic lesions [84 papillary carcinomas (PC), 38 follicular carcinomas (FC), 18 follicular adenomas, one hyalinizing trabecular tumour, f...
متن کاملMonoclonal Antibody Hbme-1 Usefulness in Differentiation of Benign Neoplasm and Differentiated Thyroid Carcinoma
HBME-l is an antimesothelial monoclonal antibody that recognizes an unknown antigen on microvilli of mesothelial cells. The antibody is only relatively specific for mesothelium and is used in the differential diagnosis of mesothelioma and adenocarcinoma within the context of an appropriate immuno-histochemical panel. HBME-l has also been reported to strongly and uniformly stain papillary and fo...
متن کاملCombination of galectin-3, CK19 and HBME-1 immunostaining improves the diagnosis of thyroid cancer
Currently, fine-needle aspiration is the most frequently used pre-operative technique for diagnosis of malignant thyroid tumors, however, pathologists are unable to reach efficient and accurate differential diagnoses between benign and malignant thyroid nodules. To aid in resolving this issue, immunohistochemistry for galectins (gal)-1, -3, -7, -8, cytokeratin 19 (CK19), Hector Battifora Mesoth...
متن کامل[Non-invasive follicular thyroid neoplasm with papillary-like nuclear features].
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced to cover a group of noninvasive encapsulated follicular-patterned thyroid lesions with very low malignant behavior. This nomination may have a great impact on the incidence of thyroid malignancy and the practice for endocrine pathologists. To demonstrate the proportion of the thyroid follicular ...
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ژورنال
عنوان ژورنال: Endocrine Journal
سال: 2003
ISSN: 0918-8959,1348-4540
DOI: 10.1507/endocrj.50.173